Objective: In this study, we aimed to investigate the effect of a self-awareness and communication techniques course on communication skills and ways of coping with stress.Method: The study was conducted in 2016. A total of 123 second-year students were included in the study. The course lasted for 14 weeks at 3 hours a week. The study was performed as pre-test and post-test. The data were collected with the Student Information Form, Communication Skills Inventory (CSI) and Ways of Coping with Stress (WCS). Lectures, slide presentations, Q&A, role-play, storytelling, humor, poetry, homework, small group work, individual work in class, reading books consistent with the course content and presenting them to the class, and watching movies and movie discussions were used during the course.Results: The students’ total CSI score and the mean post-test scores for the Mental Communication Skills and Behavioral Communication Skills subscales were higher than in the pre-test. The mean post-test score of the Self-confident Approach subscale was also higher than in the pre-test. The mean post-test score of the Unconfident Approach subscale was lower than in the pre-test. A positive correlation was found between the Behavioral Communication Skill and Submissive Approach and the Emotional Communication Skill and Social Support Seeking Approach.Conclusion: The Self-awareness and communication techniques course increased the “communication skills and self-confident approach” while decreasing the unconfident approach. The students were found to exhibit more social support seeking behavior as their emotional communication skills increased.Recommendations: We recommend the use of these methods in courses and other studies in the future.