The purpose of this study was to investigate the effects of integrated the computer modeling software in 5th-grade science curriculum on students’ science learning. According to the purpose of this study, we adopted both the quantity and quality method to gather the data including students’ science interests questionnaires classroom observations and interviews. The “plant reproduction” curriculum integrated the computer modeling software in 5th-grade science curriculum on students’ science learning. Participants were 182 5th grade students, divided 130 students in the experimental group (integrating computer modeling software into science teaching), and 52 students in the comparison group. The results showed that the computer modeling software into science teaching to enhance student learning understanding and interest. From the data showed that there were considerable student alternative conceptions in terms of learning outcomes, there were considerable injection results, to be supplemented by interviews. It found that students for the heliocentric model, and could not be abandoned. Research suggested that the use of mobile carrier as aids to enhance interest in learning. Therefore, the researchers recommended that teachers can create the boot process to explore appropriate use arguments discussed activities. It is recommended to try exploratory study students from other kinds of intelligent performance, and this element into the field of natural science learning.